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We now have coronavirus vaccines, meaning an end may be in sight for the covid-19 pandemic. But what actually is a vaccine? How do they work? And what does it take to develop a new one? In this Science with Sam video, we explore everything you need to know about vaccines and immunity, from memory cells to attenuated viruses, and why vaccines are one of the most significant medical developments in the history of the world.

Subscribe to New Scientist magazine using the discount code SAM20 – http://newscientist.com/sam20

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