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In this video we will discuss a well-constructed study looking specifically at methylprednisolone, a steroid, to prevent the progression of COVID-19 to critical respiratory disease. We will start by discussing the different steroids, mineralocorticoid and glucocorticoid functions, similarities, and differences. We will then review the evidence to date on steroids use in COVID-19, including dexamethasone, hydrocortisone, and methylprednisolone. After that, we will dive into this study that focused on pulse dosing of methylprednisolone to treat severe, but not yet critical lung disease in COVID-19. They found quite impressive results with reductions in mortality and a quicker time to recovery! Check out the video for all the details!

Link to study:
https://erj.ersjournals.com/content/early/2020/09/09/13993003.02808-2020

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Meta-analysis on Steroids in Sever COVID-19:

Study on Early Steroid Use In COVID-19:

The RECOVERY Trial on Dexamethasone in COVID-19:

How does Dexamethason work?

Inhaled Corticosteroids:

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There will be a running series of videos using the most up to date information on COVID-19, but this is an evolving field and new videos may come out that contradict that previous information. That is okay and is the nature of a fast paced and evolving clinical scenario. Stick with us as we work to unveil the intricacies of COVID-19, it’s clinical significance, and the societal implications. ***This is strictly educational and not to be mistaken as clinical recommendations, please verify all information with accepted guidelines and practice patterns.***

DISCLAIMER
THIS VIDEO DOES NOT PROVIDE MEDICAL ADVICE. The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read, watched, or listened to on this video, or any other videos, reports, texts tweets or other sources.

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