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Hundreds of volunteers are to take part in the trial of a new vaccine against coronavirus over the coming weeks, as part of a project led by scientists at Imperial College London.

Researchers at Oxford University are already conducting a separate trial of another vaccine. The studies are among more than a dozen vaccines undergoing trials around the world.

The one being developed by Imperial College uses a revolutionary new approach which means only a tiny dose should be needed. If it works the team says it should have enough vaccine to immunise 40 million people in the UK by the middle of next year.

Meanwhile leading health organisations are urging ministers to carry out a review to establish if the UK is properly prepared for another outbreak of coronavirus. The presidents of the Royal Colleges of Physicians, Surgeons, GPs and Nurses have set out their concerns in a letter published in the British Medical Journal.

In New York and the neighbouring states of New Jersey and Connecticut, they are introducing a 14-day quarantine period for visitors from 9 other US states with high rates of coronavirus infection. New cases of Covid-19 in the US have risen to their highest level since April.

Huw Edwards presents BBC News at Ten reporting by Medical Correspondent Fergus Walsh, Science Editor David Shukman and North America Editor Jon Sopel.

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